On December 10, 2022, Dr. Joseph Maroon presented his work entitled, Hyperbaric Oxygen Therapy (HBOT) – A Renaissance? at the 30th Annual World Congress of the American Academy of Anti-aging Medicine (A4M). He discussed the applications of hyperbaric oxygen for neurodegeneration, post-concussion syndrome, PTSD, stroke, post COVID cognitive impairment and enhancing peak athletic performance. At the same meeting, attended by over 5,000 people from 20 countries, he presented his work on the use of nitric oxide and hyperbaric oxygen for the treatment of TBI, stroke, aging and cognition.
Founded in 1992 by Dr. Ronald Klatz and Dr. Robert Goldman, A4M is rooted in a forward-focused mission to redefine modern medicine, The American Academy of Anti-Aging Medicine (A4M) is the established global leader for continuing medical education in longevity medicine, metabolic resilience, and whole-person care. Dr. Maroon has been the Vice President of the A4M for the last 18 years. He lectures at the annual conferences and workshops of the A4M both nationally and internationally.
In Dr. Maroon’s lecture on HBOT he discussed the physiological basis for the use of hyperbaric oxygen therapy. HBOT benefits for anti-inflammation, enhanced stem cell production and increase in various growth factors (BDNF, VEGF). He presented clinical studies and applications of HBOT for neurodegenerative conditions, traumatic brain injury, stroke, enhanced athletic performance and biomarkers of aging.
In Dr. Maroon’s preconference lecture he discussed the brain benefits of Nitric Oxide, specifically how HBOT activates the Hypoxia and Hypoxia-inducible factors (HIFs), that have numerous health benefits. These include how Hypoxia induced upregulation by HIFs to activate:
- Adaptive responses to counter metabolic, bioenergetic and redox demands
- Cells arrest temporarily in the cell cycle
- Reduce energy consumption
- Secrete survival and proangiogenic factors
- Upregulates erythropoietin (EPO) production